Your 10-year cardiovascular risk,
from a simple eye photo

Dr. Noon CVD helps your healthcare professional estimate your risk of having a first cardiovascular event, such as
a heart attack or stroke, within the next 10 years. It uses information from a photograph of your retina together with
your age and sex to provide a personalized cardiovascular risk estimate.

How It Works

Why the retina

The retina is the one part of the body where small blood vessels can be photographed directly, without needles, dye, or radiation. A retinal fundus photograph takes a few minutes and is already a routine part of eye care.

Dr. Noon CVD reads that photograph with a deep learning model trained to recognize retinal patterns associated with coronary artery calcium, a marker of atherosclerosis that is normally measured with a cardiac CT scan. (1)

The Technology

A retinal marker,
combined with age
and sex

Dr. Noon CVD uses AI to analyze patterns in your retinal photograph that are associated with coronary artery calcium. This retinal information is then combined with your age and sex to estimate your chance of having a first cardiovascular event within the next 10 years.

Dr. Noon CVD does not measure or report a coronary calcium score, and it does not replace a cardiac CT scan. Instead, it uses information found in the retina as a different way to help assess cardiovascular risk. (1)(2)

About Dr. Noon CVD

Designed to support
a broader view of your
cardiovascular risk

Dr. Noon CVD is intended for adults ages 45 to 79 who have not previously been diagnosed with atherosclerotic cardiovascular disease (ASCVD). The exam itself is simple: a healthcare professional takes a photograph of the back of your eye, which Dr. Noon CVD then analyzes.

The result is designed to support — not replace — established cardiovascular risk assessment. Your healthcare professional will consider it together with other important information about your health when evaluating your overall cardiovascular risk.

(Note: ASCVD includes nonfatal heart attacks, strokes, and related coronary issues.) (3)

REVIEW YOUR RESULTS

Understand what your results mean

Your report is designed to be clear and easy to understand, so you can better review your results and feel more prepared for discussions about next steps.

  • Your score is a probability, not a diagnosis. For example, a score of 15% means that out of 100 people with this same result, about 15 would be expected to have a heart event within the next 10 years. It is important to know that this score looks ahead—it does not mean you have heart disease right now, and it cannot detect a heart attack or stroke that is currently happening.

  • Your score places you into one of three risk groups, based on standard guidelines from the American College of Cardiology and the American Heart Association: (4)(5)

    • Low risk: score below 5%
    • Moderate risk: score from 5% up to 19.9%
    • High risk: score of 20% or higher

  • It shows where your score falls among people of similar age and sex, offering a helpful reference rather than a diagnosis.

  • It highlights lifestyle factors like activity, sleep, and weight, giving your doctor a fuller picture of your heart health beyond the score alone.

See how the test is done

References

  1. Rim TH, Lee CJ, Tham YC, et al. Deep-learning-based cardiovascular risk stratification using coronary artery calcium scores predicted from retinal photographs. Lancet Digit Health. 2021;3(5):e306-e316. PMID 33890578. DOI 10.1016/S2589-7500(21)00043-1.
  2. Lee CJ, Rim TH, Kang HG, et al. Pivotal trial of a deep-learning-based retinal biomarker (Reti-CVD) in the prediction of cardiovascular disease: data from CMERC-HI. J Am Med Inform Assoc. 2024;31(1):130-138. PMID 37847669. DOI 10.1093/jamia/ocad199.
  3. Mediwhale. Dr. Noon CVD Clinical Study Report Summary (A39) and Dr. Noon CVD Instructions for Use, Section 7.2 (IFU.US.EN.1.0, Rev. 00). MESA validation cohort, n = 4,624. On the web page, cite as “Data on file, Mediwhale, 2026” until a peer-reviewed publication is available.
  4. Arnett DK, Blumenthal RS, Albert MA, et al. 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease. Circulation. 2019;140(11):e596-e646. DOI 10.1161/CIR.0000000000000678.
  5. Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol. Circulation. 2019;139(25):e1082-e1143. DOI 10.1161/CIR.0000000000000625.